Effect of Acupoint Stimulation on Lactate During Cerebral Endovascular Intervention (ASLA)

Air Force Military Medical University of People's Liberation Army

Status: Completed

Conditions: Endovascular Procedures

Treatments: Other: sham needle; Other: electroacupuncture

Study type: Interventional

Funder types: Other

Identifiers

NCT06521645

XJH-A-20240626

Details and patient eligibility

About

It is advocated that neuroprotection should be increased before endovascular treatment and that the penumbra should be protected from reperfusion damage after recanalization. Monitoring lactate and pH levels in acute ischemic stroke patients who have had endovascular recanalization can be utilized to predict mortality and morbidity, especially in the first five hours after the procedure. This study aims to observe the effect of acupoint stimulation on lactate level during endovascular recanalization.

Enrollment: 28 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ≥18 years
• scheduled for cerebral endovascular intervention

Exclusion criteria

• American Society of Anesthesiologists status over level three
• history of cerebral vascular intervention
• history of severe neurological disease (stroke, neurological degenerative disease, psychiatric disease)
• severe hepatic or renal dysfunction
• severe glucose disorder or thyroid dysfunction
• contraindications to transcutaneous electrical stimulation (infection or injury of the skin area, implanted electrical devices)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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28 participants in 2 patient groups

Acupoint stimulation

Experimental group

Description:

needles are inserted into the skin of Baihui acupoint, and electrical acupoint stimulation is given

Treatment:

Other: electroacupuncture

Control

Sham Comparator group

Description:

needles are shallowly inserted into the skin of Bihui acupoint, but no electrical acupoint stimulation is given

Treatment:

Other: sham needle