Effect of Acute Exercise on Exosome Associated Biomarkers

Mayo Clinic

Status: Completed

Conditions: Healthy

Study type: Observational

Funder types: Other

Identifiers

NCT05541133

22-000001

Details and patient eligibility

About

This research study is being done to understand the underlying mechanism by which exercise affects the body on the cellular level, in an acute aerobic endurance setting. This may help to better understand the overall benefits of endurance exercise.

Enrollment: 12 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ages: 18 to 45 years

Exclusion criteria

• BMI >32 kg/m2. Cardiovascular, metabolic (type 2 diabetes, fasting plasma glucose at or above 110 mg/dL and untreated hypo- or hyperthyroidism) or renal disease.
• Orthopedic problems that would keep them from being able to perform an exercise. - --
• Medications that are known to affect mitochondrial function: Corticosteroids, opiates, benzodiazepines, tricyclic antidepressants, beta-blockers, sulfonylureas, insulin, anticoagulants, barbiturates, insulin sensitizers, fibrates (PPAR gamma agonist).
• Smoking.
• Pregnancy.