Effect of Aerobic Training and Moringa Oleifera on Dyslipidemia and Cardiac Endurance

Aga Khan University

Status: Unknown

Conditions: Dyslipidemias

Treatments: Other: Aerobic training and Moringa Oleifera

Study type: Interventional

Funder types: Other

Identifiers

NCT04164771

NA 125

Details and patient eligibility

About

Aerobic training is essential for maintaining and improving physical performance and has a positive effect on physiological functions as well as anthropometric characteristics. It also has positive effect on cardiovascular health and carries a number of beneficial effects on the whole body functions and systems. Aerobic training can also decrease the risk of heart disease in the individual's life.The Moringa leaves are the rich source of minerals, vitamins and other essential phytochemicals. Moringa leave have found to be very effective in many disease particularly diabetic, blood pressure, dyslipidemia and cancer.

Full description

Aerobic training is an important component for health in daily life as well as sports performance. Aerobic training improves overall health, reduces body fat, maintain body weight, resting blood pressure (systolic and diastolic), maximal oxygen consumption adequate blood supply and provision of oxygen to the body muscles .The studies reveal that aerobic training is valuable for improving cardiovascular health, fitness and quality of life. On account of lack of aerobic engagement around 17 % of the population suffer from heart related ailment, 12 % from diabetes and 10 % from breast cancer. American College of Sports Medicine suggested that 30 minutes of aerobic workout has progressive effects on physical fitness and especially on chronic diseases. Physically fit individuals have got the potential to affectively cope with stress and anxiety and coronary arteries diseases. Aerobic training can raise maximal oxygen uptake, which means body adapts to use oxygen more efficiently during physical activities. Resultantly, the heart becomes efficient and stronger; meaning that the heart doesn't have to work hard to pump blood in resting position. Aerobic training decreases resting heart rate and may increase blood volume and blood plasma. Moringa Oleifera a plant from the family Moringacea, its products are used as a health supplement introduced in Africa and south Asian countries to cure many diseases and improve health status . Moringa leaves are rich source of vitamins and protein. The Moringa oleifera leaves, flowers, seeds and pods are commonly used as vegetables diet in different regions of south Asia. Moringa plant products are sources of vitamin A, b, C and proteins, including the essential amino acids. Moringa Oleifera leaves can be merged in the feed of birds, animals and human which provide wonderful source of protein other than expensive ingredients. The Moringa oil is used in cooking products as well as for lubrication. There are scientific indications that Moringa Oleifera holds therapeutic potential for hyperlipidemia, diabetes and cardiovascular diseases. The use of herbal supplements has increased rapidly during the first decade of the twentieth century. The nutrients of Moringa are considered to be useful for disorders including skin disease, malnutrition and sexual problem.Different experimental studies has described that Moringa oleifera leaves have therapeutic potential for chronic hyperglycemia and dyslipidemia . Moringa Oleifera is used as a hypolipidemic medication to improve the lipid profile of rats fed on atherogenic diet. Moringa Oleifera intake is more effective in prevention than in treatment of hyperlipidemia.It is documented that overuse of Moringa supplements can cause high increase of iron. Hence, a daily 70 g quantity of Moringa is recommended to be batter and preventive for accumulation of nutrients.This research study is due to be conducted to determine the effect of aerobic training and Moringa Oleifera on dyslipidemia and cardiac endurance

Enrollment: 120 estimated patients

Sex: Male

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy and no medical conditions.
• LDL level should be 160-189 mg/dl
• HDL level should be < 40 mg/dl
• Tri glyceride level should be 200-499 mg/dl
• Total cholesterol level should be > 200 mg/dl).
• Beep Test score should be less than 10.5 or less than 40% vo2 max

Exclusion criteria

• Any disease condition as anemia, physical injuries, chronic disease
• Not capable of doing aerobic training

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 4 patient groups

Moringa Group

Experimental group

Description:

Participants will receive 5-7g of moringa diet daily for 6 weeks.

Treatment:

Other: Aerobic training and Moringa Oleifera

Aerobic training Group

Experimental group

Description:

Participants will receive 5-7g of moringa diet daily and will do 30 minutes of aerobic training daily for 6 weeks.

Treatment:

Other: Aerobic training and Moringa Oleifera

Moringa and Aerobic training

Experimental group

Description:

Participants will do 30 minutes of aerobic training daily for 6 weeks

Treatment:

Other: Aerobic training and Moringa Oleifera

Control Group (T4)

No Intervention group

Description:

Participants will not recieve any treatment