Effect of Age on the Success of DPC Using Bio-ceramic Materials in Cariously Exposed Teeth With Reversible Pulpitis

Postgraduate Institute of Dental Sciences Rohtak

Status: Active, not recruiting

Conditions: Pulpitis Reversible

Treatments: Procedure: DPC with BD in AGEII; Procedure: DPC with MTA in AGEI; Procedure: DPC with MTA in AGEII; Procedure: DPC with BD in AGEI

Study type: Interventional

Funder types: Other

Identifiers

NCT06240169

Harshita Wadhwa

Details and patient eligibility

About

Study Title: - Effect of age on the success of direct pulp capping using bio-ceramic materials in cariously exposed teeth with reversible pulpitis: A Prospective clinical study.

Rationale: - Preservation of pulp vitality is a critical factor in long-term tooth survival. In deep carious lesion with reversible pulpitis, vital pulp therapy procedures in the form of direct pulp capping(DPC)is more conservative treatment strategy, based on the premise that a biologically active material placed in direct contact with the pulp wound can determine the pulpal response and result in the development of a reparative hard tissue bridge to preserve pulp vitality. Patient's age may have a role in the survival rate after direct pulp capping and the role of the pulp capping material has been recognized as an important parameter for the success of treatment.

Research Question : Does age has any influence on the success of DPC procedure and is there any difference between MTA and Biodentine as DPC material in cariously exposed permanent teeth with reversible pulpitis? Aim & Objectives- To evaluate the effect of age on success of Direct Pulp Capping, to evaluate the success of MTA and Biodentine as direct pulp capping agents.

Full description

Study Title: - Effect of age on the success of direct pulp capping using bio-ceramic materials in cariously exposed teeth with reversible pulpitis: A Prospective clinical study.

Rationale: - Preservation of pulp vitality is a critical factor in long-term tooth survival. In deep carious lesion with reversible pulpitis, vital pulp therapy procedures in the form of direct pulp capping(DPC)is more conservative treatment strategy, based on the premise that a biologically active material placed in direct contact with the pulp wound can determine the pulpal response and result in the development of a reparative hard tissue bridge to preserve pulp vitality. Patient's age may have a role in the survival rate after direct pulp capping and the role of the pulp capping material has been recognized as an important parameter for the success of treatment.

Research Question : Does age has any influence on the success of DPC procedure and is there any difference between MTA and Biodentine as DPC material in cariously exposed permanent teeth with reversible pulpitis? Aim & Objectives- To evaluate the effect of age on success of Direct Pulp Capping, to evaluate the success of MTA and Biodentine as direct pulp capping agents based on clinical and radiographic findings and assessment of post operative pain for 7 days post treatment.

Statistical method: - Data analysis by suitable statistical method.

Enrollment: 174 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy patients (ASA I and ASA II).
• Patients falling in the age group of 18-60 years.
• Restorable permanent mandibular posterior teeth.
• Extremely deep caries penetrating the entire thickness of dentine and exhibiting signs and symptoms of reversible pulpitis.
• Teeth responding positively to cold test and electric pulp testing with no tenderness on percussion.

Exclusion criteria

• Primary teeth.
• Traumatic or mechanical exposure.
• No pulp exposure after caries excavation.
• Hemostasis not achieved within 10 mins.
• Teeth with irreversible pulpitis.
• Presence of periapical lesion or evidence of internal or external resorption, calcified canals, as assessed by radiographic examination.
• Patients with periodontal disease, swelling and sinus tract.
• Immunocompromised or pregnant patients, patients with any systemic disease, and a positive history of antibiotic use within 1 month and analgesic use within week before the treatment.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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174 participants in 4 patient groups

DPC in AGE I with MTA

Experimental group

Description:

DPC using MTA in Age group I i.e. 18-40years.

Treatment:

Procedure: DPC with MTA in AGEI

DPC in AGE I with BD

Experimental group

Description:

DPC using BD in Age group I i.e. 18-40years.

Treatment:

Procedure: DPC with BD in AGEI

DPC in AGE II with MTA

Experimental group

Description:

DPC using MTA in Age group II i.e. 41-60years

Treatment:

Procedure: DPC with MTA in AGEII

DPC in AGE II with BD

Experimental group

Description:

DPC using BD in Age group II i.e. 41-60years

Treatment:

Procedure: DPC with BD in AGEII