Effect of Air-tamponade on Intraretinal Cystoid Changes After Membrane Peeling

Vienna Institute for Research in Ocular Surgery

Status: Completed

Conditions: Epiretinal Membrane

Treatments: Procedure: BSS arm; Procedure: air arm

Study type: Interventional

Funder types: Other

Identifiers

NCT03457584

cysMP

Details and patient eligibility

About

Patients with intraretinal cystoid changes before scheduled membrane peeling for epiretinal membranes are included. Patients are randomized for balanced salt solution (BSS) or air-tamponade.

Full description

Patients with intraretinal cystoid changes before scheduled membrane peeling for epiretinal membranes are included. 23G-pars plana vitrectomy with membrane peeling is performed in all patients. Before surgery patients are randomized for BSS or air-tamponade. Optical coherence tomography (OCT) is performed 5 days after and 3 months after surgery, visual acuity is measured 3 months after surgery.

Enrollment: 96 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• epiretinal membranes and intraretinal cystoid changes

Exclusion criteria

• macular edema due to other reason than epiretinal membrane
• hereditary ocular disease
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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96 participants in 2 patient groups

BSS arm

Active Comparator group

Description:

BSS is given at the end of surgery

Treatment:

Procedure: BSS arm

air arm

Experimental group

Description:

air-tamponade is given at the end of surgery

Treatment:

Procedure: air arm