Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant

Kafrelsheikh University

Status: Enrolling

Conditions: Immediate Implant Placement

Treatments: Procedure: Immediate Implant Placement and L-PRF; Procedure: Immediate Implant Placement and Alb-PRF

Study type: Interventional

Funder types: Other

Identifiers

NCT06863051

KFSIRB200-531

Details and patient eligibility

About

The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.

Full description

The objective of this study will be to compare between xenograft with Alb-PRF gel and xenograft with L-PRF ( L-PRF Block ) in the aspects of :

• Peri-implant vertical defect depth.
• Crestal bone level.
• Bucco-lingual bone width.
• Keratinized tissue width

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

1. Inclusion criteria

   • The presence of non-restorable mandibular molar.
   • Patient 18-45 years old
   • Intact buccal and lingual walls
   • Good oral hygiene.
   • Prescence of sufficient restorative space.
   • Jumping gap more than 2 mm.

2. Exclusion criteria

   • Proximity of anatomical structures
   • Acute localized infection (suppuration at the surgical field)
   • Patients on chemotherapy or radiotherapy.
   • Patients who have systemic disorders (diseases) {diabetes mellitus, autoimmune disease, ...etc},
   • Pregnant patients.
   • Smoking and Alcohols.
   • Presence of periapical pathology affecting the neighboring teeth.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Albumin-PRF group

Experimental group

Description:

Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel

Treatment:

Procedure: Immediate Implant Placement and Alb-PRF

L-PRF group

Experimental group

Description:

Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF ( L-PRF Block )

Treatment:

Procedure: Immediate Implant Placement and L-PRF