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Effect of Aloe Vera Gel as an Intra Canal Medicament

I

Islamabad Medical and Dental College

Status

Completed

Conditions

Periapical Diseases

Treatments

Biological: Aloe vera Gel

Study type

Interventional

Funder types

Other

Identifiers

NCT06243601
IslamabadDentalHospital

Details and patient eligibility

About

This research will overview the effect of aloe vera gel (AVG) as intra canal medicament in patients with asymptomatic periapical lesions. It will provide endodontists with scientific evidence regarding the beneficial use of AVG as an intracanal medicament owing to its superior antibacterial and analgesic properties as compared to routinely used commercial intra canal medicaments.

Full description

Objective: To evaluate the effect of aloe vera gel based on clinical signs and symptoms as an intracanal medicament in asymptomatic periapical lesions over a period of three weeks. Methodology: Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions in group A while in group B (control group) no intracanal medicament will be placed. Patients will be randomly divided into two groups by randomization in Statistical Package for Social Sciences software (SPSS v24.0). They will be recalled for one week and three week follow ups and in case of no clinical signs and symptoms endodontic procedure will be completed. Statistical analysis: Descriptive statistics will be used for reporting age. Frequencies and percentages will be calculated for categorical variables and intergroup comparison will be done by chi square test

Enrollment

60 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Both male and female patients presenting with asymptomatic periapical lesions in permanent teeth

Exclusion criteria

  • History of allergy to AVG

    • Comorbidities likely to impair healing
    • Pregnant women
    • History of previous endodontic treatment in the same tooth
    • Presence of pulp calcification
    • Internal or external root resorption

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Sequential Assignment

Masking

Single Blind

60 participants in 2 patient groups

Intervention Group
Experimental group
Description:
Fresh AVG will be prepared. It will be placed as intracanal medicament after cleaning and shaping in patients with asymptomatic periapical lesions
Treatment:
Biological: Aloe vera Gel
Control Group
No Intervention group
Description:
No intracanal medicament will be placed

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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