Effect of Ambient Light on the Parameters of the Pupillary Light Reflex

University of Medicine and Dentistry of New Jersey

Status: Completed

Conditions: Healthy Volunteers

Treatments: Other: Pupillometry

Study type: Observational

Funder types: Other

Identifiers

NCT01207817

0120090181

Details and patient eligibility

About

The purpose of this study is to determine the effects of varying luminescent levels on the pupillary response.

Full description

Evaluation of the pupillary response is an underemphasized aspect of the assessment of visual function. The pupillary light reflex is one of the few objective indicators of afferent input from the retina and optic nerve. Since the pupillary light reflex is processed through the retina, it may be used to assess visual integrity (1). Pupillometry is a reliable technology capable of providing repetitive data on quantitative pupillary function in states of health and disease (2). Amplitude, latency, maximum constriction velocity, mean constriction velocity, and dilation velocity are measured using the Neuroleptics pupillometer. The effects of varying levels of ambient light on these parameters of the pupillary response have not been extensively studied. The purpose of this investigation is to determine the effects of varying luminescent levels on the pupillary response.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers

Exclusion criteria

• recent bout of conjunctivitis or infection in the eye recent eye surgery seizure disorder unable to lie flat for 30 minutes known history of eye disease which cannot be corrected with lenses

Trial design

30 participants in 1 patient group

no condition

Description:

no condition - healthy volunteers

Treatment:

Other: Pupillometry