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In this study, Amlodipine has been used to study its effects in newly diagnosed hypertensive patients.
Full description
The incidence of hypertension is on the rise in developing countries like Pakistan. Different medications are used to decrease blood pressure with Amlodipine as one of the first-line drugs. It was proposed that due to interaction with calcium and thus luminal cholecystokinin releasing factor; Amlodipine might increase the cholesterol level and thus cause dyslipidemia.
Objective: In this regard, this study was conducted to look into the effects of Amlodipine in newly diagnosed cases of hypertension that had received no medication previously.
Methodology: Experimental study with a healthy control group with the sample size calculated out to be 80, comprising of an equal number of enrolment into case and control groups.
Enrollment
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Volunteers
Inclusion and exclusion criteria
Inclusion criteria for cases.
Newly diagnosed mild to moderate hypertensive. (2) Non-obese individuals. 3) Must not have received antihypertensive treatment previously. 4) Has elevated serum cholesterol levels. Exclusion criteria for cases
Any other major illness.
Inclusion criteria for controls
Primary purpose
Allocation
Interventional model
Masking
80 participants in 2 patient groups
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Data sourced from clinicaltrials.gov
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