Effect of an Apomorphine Pump on the Quality of Sleep in Parkinson's Disease Patients (POMPRENELLE).

Fondation Ophtalmologique Adolphe de Rothschild

Status and phase: Terminated; Phase 4

Conditions: Parkinson's Disease

Treatments: Drug: Apomorphine

Study type: Interventional

Funder types: NETWORK

Identifiers

NCT02688465

CHH_2016_01

Details and patient eligibility

About

Parkinson's disease is not only a pathology of movements. There are many non-motor symptoms that complicate and impair patients' quality of life. Among those disorders are sleep disorders.

Insomnia is the most frequent symptom. Most patients report 2-5 awakenings per night and long periods of awakening which occupy 30 to 40% of their night.

Apomorphine is a dopamine agonist that may be administered with a pump . The objective of the study is to assess changes in the quality of sleep in Parkinson's disease patients treated with an apomorphine pump.

Enrollment: 15 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parkinson's disease patients for whom a treatment with an apomorphine pump is indicated

Exclusion criteria

• atypical parkinsonian syndrome
• cognitive impairment
• pregnancy
• breast feeding
• patient under a legal protection procedure
• patient denying to participate to the study
• lack of affiliation to a social security system

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Apomorphine pump

Experimental group

Treatment:

Drug: Apomorphine