Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy

University of Thessaly

Status: Enrolling

Conditions: Pancreatic Cancer Resectable; Pancreatectomy; Enhanced Recovery After Surgery

Treatments: Other: enhanced recovery after surgery

Study type: Observational

Funder types: Other

Identifiers

NCT06935448

UNIVERSITY OF THESSALY 2412

Details and patient eligibility

About

This study assesses whether patients with pancreatic cancer who undergo surgery experience improved outcomes following the implementation of a multidisciplinary care pathway, specifically an enhanced recovery after surgery (ERAS) program.

This pathway includes various interventions in the preoperative, intraoperative, and postoperative care of these patients, all aimed at enhancing their health status and postoperative results.

Full description

This prospective observational study is conducted by the same surgical team at two high-volume pancreatic cancer referral centers in Greece.

Patients undergoing elective pancreatic surgery are prospectively enrolled and managed according to a standardized ERAS protocol (ERAS group).

A control group, which received standard perioperative care before the implementation of ERAS, was retrospectively selected and matched based on demographic and clinical parameters.

The primary study endpoint is the length of hospital stay (LOS), while secondary endpoints include 30-day mortality and morbidity.

Enrollment: 170 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients
• diagnosis of pancreatic cancer
• elective open pancreatic surgery

Exclusion criteria

• age <18 years
• emergency pancreatic surgery
• other surgical procedures
• missing data
• lost to follow-up

Trial design

170 participants in 2 patient groups

Control group

Description:

traditional perioperative care

ERAS group

Description:

enhanced recovery after surgery perioperative care

Treatment:

Other: enhanced recovery after surgery