Effect of an Exercise Bout in Plasma and Fecal Profile (MEMEX)

European University

Status: Completed

Conditions: Healthy

Treatments: Other: Prolonged Exercise session

Study type: Interventional

Funder types: Other

Identifiers

NCT04244149

UEM0003

Details and patient eligibility

About

The aim of this project is to study the effect of a bout of exercise on the metabolomic profile of plasma and feces as well as its influence on the intestinal microbiota.

Full description

The practice of physical exercise has numerous health benefits, preventing the appearance and development of cardiovascular diseases and various types of cancer. Exercise causes changes in the vascular, muscular and pulmonary systems, etc. One of the benefits that can result from exercise modification of the intestinal microbiota and its metabolic profile. In order to identify the potential changes that exercise has on the intestinal microbiota and its metabolic profile, the purpose of this study is to identify changes in the plasma and fecal metabolome and in fecal microbiota associated with a bout of exercise

Enrollment: 40 patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-45 years of age
• high physical condition (VO2 ≥ 55 ml/kg/min)
• BMI 18-25 kg/m2

Exclusion criteria

• antibiotics intake during 3 months prior to the study,
• smoking
• nutritional complements
• ergogenic complements
• prebiotics
• probiotics
• vegetarian or vegan diet
• chronic medication
• gastrointestinal surgery
• Any diagnosed disease

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Intervention group

Experimental group

Description:

Participants will exert an exercise prolonged session

Treatment:

Other: Prolonged Exercise session