Effect of an Internet-based At-home Physical Training Protocol on Quality of Life, Fatigue, Functional Performance, Aerobic Capacity and Muscle Strength in Multiple Sclerosis Patients (ms-intakt)

University of Erlangen-Nürnberg

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Behavioral: e-training; Other: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT02771652

1.01.1/09/007

Details and patient eligibility

About

In this randomised controlled trial, the feasibility and effectiveness of an internet-based exercise intervention including progressive strength and endurance training (e-training) for PwMS was investigated. Primary outcome was health-related quality of life, secondary outcomes were muscle strength, aerobic capacity and lung function, physical activity and fatigue.

Enrollment: 126 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosed Multiple Sclerosis (McDonald criteria),
• an EDSS score of less than or equal to 4.0,
• not less than 4 weeks of clinical stability prior to inclusion in the study,
• access to the internet.
• the taking of immunotherapeutic agents was not relevant and not monitored

Exclusion criteria

• primary progressive multiple sclerosis
• clinically relevant internal disease, especially cardiovascular or pulmonary disease, metabolic and orthopedic diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

126 participants in 2 patient groups

e-training intervention

Active Comparator group

Description:

Resistance and endurance training

Treatment:

Behavioral: e-training

Control

Other group

Description:

no exercise

Treatment:

Other: Control