EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL

Erzincan University

Status: Unknown

Conditions: MINI MENTAL STATE EXAMINATION TEST; NEURON SPECIFIC ENOLASE; Postoperative Cognitive Dysfunction

Treatments: Behavioral: POSTOPERATIVE COGNITIVE DYSFUNCTION

Study type: Observational

Funder types: Other

Identifiers

NCT04279132

19/10

Details and patient eligibility

About

The aim of this study is to compare the effects of total intravenous anesthesia and inhalation anesthesia methods on postoperative cognitive dysfunction according to Mini Mental State Examination scores and Neuron Specific Enolase levels in lumbar disc herniectomy operations.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-Lumbal disc herniectomy operation 18-65 age

Exclusion criteria

• Patients before and after the coronary artery bypass graft surgery
• patients in the last trimester of pregnancy
• patients with severe heart failure
• liver failure
• kidney failure
• malignant hyperthermia
• lactating patients
• patients with vision or hearing problems
• patients having difficulty in understanding and speaking Turkish
• Parkinson's and Alzheimer's disease
• alcohol and drug addicts
• morbidly obese patients
• intraoperative hypotension, hypertension and hypoxemia

Trial design

80 participants in 2 patient groups

TOTAL INTRAVENOUS ANESTHESIA

Treatment:

Behavioral: POSTOPERATIVE COGNITIVE DYSFUNCTION

INHALATION ANESTHESIA

Treatment:

Behavioral: POSTOPERATIVE COGNITIVE DYSFUNCTION