Effect of APC and Epo on the Inflammatory Response During Sepsis

Lawson Health Research Institute

Status: Completed

Conditions: Systemic Inflammation; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT00229034

11652E

R-05-382

Details and patient eligibility

About

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis.

Full description

An observational study to determine the effect of APC and Epo in reducing the systemic inflammatory response during severe sepsis. Patients already prescribed either drug will be enrolled. The microcirculation of the sublingual vascular bed will be observed with a microscope to detect the alterations in the inflammatory response.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients in the ICU in severe septic shock undergoing APC and/or Epo treatment

Exclusion criteria

• any severe comorbid conditions