Effect of Atorvastatin Administration Before Primary Percutaneous Coronary Intervention

Samsung Medical Center

Status: Completed

Conditions: Angioplasty, Transluminal, Percutaneous Coronary

Treatments: Drug: atorvastatin

Study type: Interventional

Funder types: Other

Identifiers

NCT00610870

2007-04-049

Details and patient eligibility

About

The purpose of this study to determine whether statin pretreatment decrease myocardial infarct size in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.

Enrollment: 173 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Presence of chest pain for more than 30 minutes but less than 12 hours after symptom onset
• ST segment elevation more than 1 mm in two or more contiguous leads or presumably a new onset left bundle branch blockage

Exclusion criteria

• Cardiogenic shock
• History of myocardial infarction
• Chronic liver disease
• Previous or current statin use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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173 participants in 2 patient groups

1

Experimental group

Description:

Atorvastatin group

Treatment:

Drug: atorvastatin

2

No Intervention group

Description:

Control group