Effect of "Autogenous Leukocyte Platelet Rich Fibrin- Tooth Graft" Combination Around Immediately Placed Implants

Dalia Rasheed Issa

Status

Completed

Conditions

Autogenous Tooth Bone Graft

L-PRF

Immediate Implant Placement

Treatments

Combination Product: immediate implant placement with ATBG

Combination Product: immediate implant placement with ATBG and L-PRF

Study type

Interventional

Funder types

Other

Identifiers

NCT04795102

KD/03/20

Details and patient eligibility

About

Immediate implant placement into fresh extraction sockets is gaining popularity because of fewer clinical procedures and maintenance of bone architecture compared to conventional methods, thus reducing the treatment time and increasing patient satisfaction. In addition, the survival rate of the immediate implantation is comparable to that of the healed implantation sites. Recently, ATBG made from compromised teeth was applied in bone defects and resulted in a good clinical efficacy. Moreover, it is more accepted by patients to use extracted teeth as a bone graft material, especially in the case of immediate implant placement. In 2020, Kizildağ and coworkers studied the outcome of PRF as an adjunct with ATBG on bone healing in rabbit peri-implant osseous defects. They reported that combination of ATBG with PRF contributed to significantly higher new bone formation and better bone/implant contact in rabbits with peri-implant bone defects. The main hypothesis behind this study is that using L-PRF with ATBG following immediate implant placement could promote stabilization of graft particles and enhance new bone formation with a shorter time. Therefore, the purpose of this study was to compare the clinical and radiographic outcomes of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth.

Enrollment

26 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Teeth need to be extracted for periodontal reasons with a defect of labial bone (horizontal or vertical bone defect).
the teeth without acute inflammation.
no uncontrolled systemic disease which is not suitable for implantation.
Good systemic and oral health.

Exclusion criteria

patients with systemic diseases or medications known to alter healing processes
Psychiatric disorders.
Root canal treated teeth.
patients undergoing or who had undergone radiation therapy and chemotherapy to the head and neck region during 12 months.
patients with para-functional habits.
alcoholics.
drug abusers.
heavy smokers