Effect of Bacopa Monnieri on Working Memory and Cognitive Processing in Student

Khon Kaen University

Status and phase: Completed; Phase 1

Conditions: Healthy

Treatments: Dietary Supplement: Bacopa Monnieri 300 mg/day; Dietary Supplement: Placebo; Dietary Supplement: Bacopa Monnieri 600 mg/day

Study type: Interventional

Funder types: Other

Identifiers

NCT02931747

HE581418

Details and patient eligibility

About

The purpose of this study is to determine the effect of Bacopa Monnieri on working memory and cognitive processing in student.

Full description

Learning and working memory are two of the key role for studying and work successful for student particular the high school student who study hard and preparing themselves for the graduate study. The consumption of brain booster product or functional food for improving memory has gained much attention. It has been reported that Bacopa Monnieri could improve learning and working memory in elderly subject by improving the N100 and P300 event related potential. Therefore, Bacopa Monnieri might be the potential product for improving the learning and working memory in student particular high school student.

Enrollment: 75 patients

Sex: All

Ages: 15 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy student subject aged between 15-18 years old who studying in the school within Khon Kaen province.
• Body mass index is between 18.5-24.9

Exclusion criteria

• Subjects who are diagnosed with one of the following: cardiovascular diseases, respiratory disease, neuropsychological diseases, head injury, diabetes mellitus, liver disease, cancer, autoimmune disease and hematological disorder are excluded.
• Subjects who take any medicine or nutraceuticals or hormone that effect on central nervous system are excluded.
• Alcohol addict or smoking addiction (more than 10 pieces/day)
• Athlete or subjects who have a regular exercise more than 3 times/week
• Subjects who don't follow the instruction during the trial
• Subjects who are participating the other project.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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75 participants in 3 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Subjects are received the pill of placebo which has same color, shape and smell like the Bacopa Monnieri once daily for 16 weeks.

Treatment:

Dietary Supplement: Placebo

Bacopa Monnieri 300 mg/day

Active Comparator group

Description:

Subjects are received the pill of Bacopa Monnieri at the dose of 300 mg/day once daily for 16 weeks

Treatment:

Dietary Supplement: Bacopa Monnieri 300 mg/day

Bacopa Monnieri 600 mg/day

Active Comparator group

Description:

Subjects are received the pill of Bacopa Monnieri at the dose of 600 mg/day once daily for 16 weeks

Treatment:

Dietary Supplement: Bacopa Monnieri 600 mg/day