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To compare the direct effect of sodium acetate ringer injection or albumin on volume expansion in shock patients, and to provide reference for volume resuscitation strategy in shock patients
Full description
CI/SVI increase amplitude and maintenance time
Enrollment
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Inclusion criteria
Age ≥ 18 years old, gender unlimited
Shock requires volume resuscitation:
Insufficient tissue perfusion: wet and cold skin, decreased urine volume (<0.5ml/kg/h), change of consciousness, blood lactate >2.0mmol/l or vasoactive drugs are required to maintain map>65mmhg
Presence of volume reactivity: (under controlled ventilation) PPV ≥ 15% or passive leg raising test (+) or (under controlled ventilation) IVC variability ≥ 18% or the presence of volume reactivity as judged by clinicians
The patient has no obvious restlessness, RASS ≤ 0
The legal representative of the subject signs the informed consent form-
Exclusion criteria
Primary purpose
Allocation
Interventional model
Masking
500 participants in 2 patient groups
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Central trial contact
Yun Long, doctor
Data sourced from clinicaltrials.gov
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