Effect of Barley Supplemented Wheat Bread on Markers of Cardiovascular and Renal Health

K

Khyber Medical University Peshawar

Status

Completed

Conditions

Kidney Diseases
Cardiovascular Diseases

Treatments

Other: Effect of Barley Supplemented Wheat Bread on markers of Cardiovascular and Renal Health

Study type

Interventional

Funder types

Other

Identifiers

NCT05312788
ASRB001313/EB/IBMS

Details and patient eligibility

About

The disruption of colonic microbiota has been linked to a number of diseases, mainly cardiovascular and kidney diseases. One possible means to improve the microbiota is to increase dietary fiber intake as the intake of dietary fiber shifts the fermentation from proteolytic saccharolytic fermentation. Beta-glucans are soluble dietary fibers mainly found in oats and barley. Results from previous studies suggest that the consumption of barley reduces the risk of cardiovascular and kidney diseases. Therefore, this study will explore the effect of barley beta-glucans on markers of Cardiovascular and Renal health.

Enrollment

25 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy individuals of age 18 years or older
  • BMI ranged between 18.5 and 24.9

Exclusion criteria

  • Celiac disease, Cancer, Diabetes , cardiovascular diseases
  • Gastro intestinal tract disease
  • Pregnant women
  • Use of pre-, pro- or antibiotics 15 days before the enrollment into the study
  • Food allergy to food used in the trial

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

25 participants in 2 patient groups, including a placebo group

Whole wheat bread
Placebo Comparator group
Description:
Whole wheat bread will be used as control bread.
Treatment:
Other: Effect of Barley Supplemented Wheat Bread on markers of Cardiovascular and Renal Health
Barley supplemented wheat bread
Experimental group
Description:
Barley supplemented wheat bread (50% substitution) will be used as experimental bread.
Treatment:
Other: Effect of Barley Supplemented Wheat Bread on markers of Cardiovascular and Renal Health

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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