Effect of Beans Compared to Beef on Satiety in Older Adults

University of Guelph

Status: Completed

Conditions: Older Adults

Treatments: Other: Extra-lean ground beef; Other: Canned red kidney beans, drained and rinsed; Other: Canned black beans, drained and rinsed

Study type: Interventional

Funder types: Other

Identifiers

NCT05499819

REB-22-03-028

Details and patient eligibility

About

This human clinical trial is using a randomized crossover design to examine the effect of two varieties of beans compared to beef on satiety and food intake in older adults.

Full description

This human clinical trial is using a randomized crossover design that includes 3 study visits separated by washout periods of at least 1 week. Each study visit will last approximately 4 hours and will occur at the Human Nutraceutical Research Unit (HNRU) at the University of Guelph. Study visits will occur in the morning and begin with measurement of fasting body weight. Participants will then complete a baseline satiety questionnaire before they consume a breakfast test meal (that includes either red kidney beans, black beans or extra-lean ground beef). After the breakfast meal, participants will complete a palatability questionnaire. They will also complete more satiety questionnaires at 15, 30, 45, 60, 120, 150 and 180 minutes. After 180 minutes, participants will be consume an ad libitum pizza lunch meal until they are comfortably full. Participants will then be sent home with a food scale and instructions to record everything they eat and drink for the remainder of the day.

Enrollment: 35 patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy males and females
• ≥60 years old
• BMI between 18.5-30 kg/m2

Exclusion criteria

• Medication use that is not at a stable dose (at least 3 months)
• Natural health product use that is not at a stable dose (at least 3 months)
• Antibiotic use in the past 3 months
• Overnight shift work
• Alcohol consumption >14 drinks/week or >4 drinks/sitting
• Anaphylactic food allergy
• Pulse (beans, lentils, chickpeas, dried peas) consumption >4 servings per week
• Recent or intended significant weight loss or weight gain (>4 kg in previous 3 months)
• Breakfast skipping ≥4 days per week
• Vegan diet
• Dislike or unable to consume beans, ground beef, shredded cheddar cheese, white tortilla wraps or frozen cheese pizza
• Three Factor Eating Questionnaire scale scores >11 for Cognitive Restraint, >9 for Disinhibition, and >8 for Hunger
• Diagnosed hypertension (blood pressure >140/90mmHg) that is not managed
• Diagnosed digestive-related condition (i.e. Celiac Disease, constipation, gastritis, gastroesophageal reflux disease, gluten intolerance, hemorrhoids, inflammatory bowel disease (Crohn's, Ulcerative Colitis), irritable bowel syndrome, lactose intolerance)
• Diagnosed cognitive-related condition (i.e. Alzheimer's Disease, amnesia, dementia, generalized anxiety disorder, major depressive disorder, Parkinson's Disease, schizophrenia, traumatic brain injury)
• Medical condition that does not have stable management for at least 3 months
• Medical or surgical event requiring hospitalization in the past 3 months
• Tobacco use
• Cannabis use
• Vape use

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

35 participants in 3 patient groups

Black beans

Experimental group

Description:

Canned black beans, drained and rinsed

Treatment:

Other: Canned black beans, drained and rinsed

Red kidney beans

Experimental group

Description:

Canned red kidney beans, drained and rinsed

Treatment:

Other: Canned red kidney beans, drained and rinsed

Extra-lean ground beef

Experimental group

Description:

Extra-lean ground beef, pan-fried

Treatment:

Other: Extra-lean ground beef