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Effect of Beta-Alanine on Heart Rate Response

University of North Carolina (UNC) logo

University of North Carolina (UNC)

Status

Completed

Conditions

Fatigue
Exercise

Treatments

Dietary Supplement: Beta-alanine
Dietary Supplement: Placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT01745016
12-1787

Details and patient eligibility

About

Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine the effectiveness of beta-alanine supplementation. The physical working capacity test has been used to show significant increases in physical working capacities following supplementation. The physical working capacity tests were originally developed by Moritani et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is hypothesized that beta-alanine will increase physical working capacity at heart rate threshold, thereby signifying a delay in fatigue.

Full description

An equal number of men and women will be recruited [Men, n=20 (10 placebo [PL]; 10 beta-alanine (Active)]; [Women,n=20 (10 PL; 10 Active)]. Men and women will be randomly assigned to respective groups to allow for equal numbers in supplement and placebo groups.

Enrollment

35 patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • Between the ages of 18-35 years old
  • Be recreationally active (defined as accumulating 1-5 hours of moderate intensity

Exclusion Criteria

  • Any health risks or indicators that would prevent them from participating in physical activity, as determined by a health history questionnaire
  • Must not have taken performance enhancing supplements containing beta-alanine or creatine during the last 3 months

Trial design

35 participants in 2 patient groups, including a placebo group

Placebo
Placebo Comparator group
Description:
placebo
Treatment:
Dietary Supplement: Placebo
Beta-Alanine
Experimental group
Description:
beta-alanine
Treatment:
Dietary Supplement: Beta-alanine

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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