Effect of Bleaching Regimen With Different Activation Modes on Color Stability, Surface Roughness, Tooth Sensitivity and Patient Satisfaction

Tanta University

Status: Invitation-only

Conditions: Bleaching Efficacy; Bleaching Sensitivity; Bleaching; Satisfactory

Treatments: Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation; Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only; Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation

Study type: Interventional

Funder types: Other

Identifiers

NCT07493941

Dental Bleaching

Details and patient eligibility

About

The purpose of this study was to conduct a randomized double-blind clinical trial to examine the efficacy of an in-office bleaching regimen with varied activation modes on color stability, surface roughness, tooth sensitivity, and patient satisfaction.

Full description

Tooth discoloration is a common esthetic concern that can negatively impact patients' self-confidence and quality of life. Contemporary restorative dentistry increasingly emphasizes minimally invasive approaches, with vital tooth bleaching emerging as a widely accepted, conservative treatment for managing extrinsic and intrinsic discoloration. The effectiveness of bleaching procedures primarily depends on the oxidative degradation of chromogenic compounds within dental hard tissues, leading to improved tooth color.

In-office bleaching techniques often incorporate various activation modes intended to enhance the efficacy of bleaching agents, accelerate treatment time, and improve clinical outcomes. These activation methods may include light-emitting diode (LED) systems, laser activation, or purely chemical activation without external energy sources. Despite their widespread use, the actual benefit of these activation modalities remains controversial, with conflicting evidence regarding their influence on bleaching effectiveness and associated adverse effects.

Enrollment: 45 estimated patients

Sex: All

Ages: 20 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged 20-35 years
• Individuals seeking esthetic improvement through tooth bleaching
• Good general and oral health, with no active periodontal disease
• Normal vital teeth (confirmed by clinical examination)

Exclusion criteria

• Teeth with caries, cracks, hypersensitivity, restorations, veneers, or crowns in the anterior region
• Pregnant or lactating women
• Smoking or use of tobacco products

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 3 patient groups

Laser-Activated In-Office Bleaching

Experimental group

Description:

Participants receive in-office bleaching using 35% hydrogen peroxide activated by a dental laser system.

Treatment:

Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with Laser Activation

Light-Activated In-Office Bleaching

Experimental group

Description:

Participants receive in-office bleaching using 35% hydrogen peroxide activated by a visible light source

Treatment:

Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) with LED/Light Activation

Chemically Activated In-Office Bleaching (Control)

Active Comparator group

Description:

Participants receive in-office bleaching using 35% hydrogen peroxide without any external activation.

Treatment:

Other: 35% Hydrogen Peroxide Bleaching Gel (Bleach 'n Smile®, Schutz Dental, Germany) - Chemical Activation Only