Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures (BMIORTHO)

American University of Beirut Medical Center

Status: Completed

Conditions: Orthopedic Procedures; Obesity

Treatments: Procedure: Orthopaedic surgery

Study type: Observational

Funder types: Other

Identifiers

NCT04827888

20210330BMI

Details and patient eligibility

About

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries using a retrospective cohort study design. The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities.

Full description

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the procedure specific, independent-effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries.

The study is a retrospective cohort study. The subjects will be the individuals undergoing one of first 25 most commonly performed orthopedic surgeries, whose information is derived form the de-identified patients' data collected through the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. The primary outcome will be composite post-operative morbidity. Specific morbidities will also be evaluated including cardiovascular, vascular and renal complications, length-of-stay (LOS), and the need for re-intervention and readmission, as well as 30-day mortality. Descriptive statistics and multivariable regression models will assess the independent-effect of BMI on outcomes.

The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities. The surgeon will be able to better counsel obese patients and devise a better surgical plan to prevent or deal with the expected outcomes.

Enrollment: 76,189 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The inclusion and exclusion criteria are the same as that of ACS-NSQIP database.
• All patients who have undergone any of the 25 most common orthopedic procedures as primary procedure as identified through the CPT codes

Exclusion criteria

• All patients whose BMI was not reported

Trial design

76,189 participants in 5 patient groups

underweight

Description:

patients who underwent one of the 25 common orthopaedic surgeries and have a body mass index (BMI) of \<18.5kg/m2

Treatment:

Procedure: Orthopaedic surgery

normal-weight

Description:

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI between 18.5kg/m2 and 24.9kg/m2

Treatment:

Procedure: Orthopaedic surgery

overweight

Description:

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI between 25kg/m2 and 29.9kg/m2

Treatment:

Procedure: Orthopaedic surgery

mildly obese

Description:

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI between 30kg/m2 and 34.9kg/m2

Treatment:

Procedure: Orthopaedic surgery

moderately-to-severely obese

Description:

patients who underwent one of the 25 common orthopaedic surgeries and have a BMI ≥35kg/m2

Treatment:

Procedure: Orthopaedic surgery