Effect of Camel Milk on Insulin and Incretin Response

Imperial College London Diabetes Centre

Status: Unknown

Conditions: Glucose Tolerance; Insulin Sensitivity

Treatments: Dietary Supplement: Cow milk; Dietary Supplement: Camel milk

Study type: Interventional

Funder types: Other

Identifiers

NCT03725969

IREC033

Details and patient eligibility

About

To examine the differential effect of camel and cow milk on the physiological response, to a liquid mixed-meal challenge, in people with normal glucose tolerance

Full description

Camel milk is used as a traditional remedy throughout the Middle East and Indian Subcontinent for conditions such as type 2 diabetes and dyslipidemia. It is currently unclear how such an effect could be mediated in vivo and studies are limited. We performed this study as a pilot experiment to assess the effects of camel milk on Insulin, Glucose, GLP-1, C-peptide and Lipid profile.

Enrollment: 15 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal glucose tolerance
• BMI < 30 kg/m2

Exclusion criteria

• Type 1 diabetes mellitus
• Type 2 diabetes mellitus
• Impaired fasting glucose or impaired glucose tolerance
• Lactose intolerance
• Weight loss / gain ≥ 5 kg in the preceding two months
• Use of estrogenic drugs or corticosteroids
• Known hypertriglyceridemia requiring treatment
• History of heart attack, angina or cardiovascular disorder
• History of malignant tumor
• Pregnant or lactating women
• Hemoglobin < 12 for any reason
• Recent surgery or major hemorrhage
• History of bariatric or metabolic surgery

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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15 participants in 2 patient groups

Healthy individuals (camel milk)

Experimental group

Treatment:

Dietary Supplement: Camel milk

Healthy individuals (cow milk)

Experimental group

Treatment:

Dietary Supplement: Cow milk