Effect of Carotid Ultrasound-guided Fluid Management on Anesthetic-induced Hypotension in Elderly Patients Undergoing Gastrointestinal Surgery

Min Su

Status: Enrolling

Conditions: Hypotension on Induction

Treatments: Other: Fluid therapy under the guide of Carotid ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT05891951

2023197

Details and patient eligibility

About

The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal surgery.

The main question[s] it aims to answer are:

Whether fluid therapy reduces the incidence of general anaesthesia induced hypotension in elderly patients undergoing gastrointestinal surgery.

Whether carotid ultrasound can guide fluid management in elderly patients undergoing gastrointestinal surgery.

Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient, anesthesia will be then induced. If volume is sufficient, anesthesia will be directly induced. There is a comparison group: No carotid ultrasound will be used to assess the volume status of the patients, and anesthesia will be directly induced.

Enrollment: 150 estimated patients

Sex: All

Ages: 60 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 60-80 years old
• gender unlimited
• ASA: Grade I-Ⅲ
• BMI:18-30kg/㎡
• Patients undergoing elective gastrointestinal surgery under general anesthesia Informed consent

Exclusion criteria

• Carotid artery stenosis ≥50%
• Patients with heart valve disease
• Patients with left ventricular ejection fraction < 50%
• Patients with cardiac dysfunction (NYHA grade Ⅲ-Ⅳ and/or NTproBNP≥900pg/ml)
• Patients Combined with renal insufficiency (creatinine ≥178μmol/L, and/or blood urea nitrogen > 9mmol/L)
• Preoperative systolic blood pressure> 160mmHg or diastolic blood pressure > 100mmHg
• Refuse to participate in the test
• Patients participating in other clinical trials

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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150 participants in 2 patient groups

B-Carotid ultrasound guided fluid therapy

Experimental group

Description:

Participants will use carotid ultrasound to assess volume status. If volume is insufficient, fluid therapy will be selected until volume is sufficient, anesthesia will be then induced. If volume is sufficient, anesthesia will be directly induced.

Treatment:

Other: Fluid therapy under the guide of Carotid ultrasound

C-No intervention

No Intervention group

Description:

No carotid ultrasound will be used to assess the volume status of the patients, and anesthesia will be directly induced.