Effect of Celecoxib on Transitional Pain After Outpatient Surgery

Lawson Health Research Institute

Status and phase: Withdrawn; Phase 4

Conditions: Pain

Treatments: Drug: placebo; Drug: celebrex

Study type: Interventional

Funder types: Other

Identifiers

NCT00664690

10457

R-04-309

Details and patient eligibility

About

Sixty adults having shoulder and forearm surgery will receive either placebo or celebrex started preoperatively and continued for 3 days. Rescue medications required as well as pain scores will be assessed using a patient diary to evaluate the effect of celebrex in controlling transitional pain

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for elective ambulatory surgery of the shoulder
• ASA I - III
• Able to read English
• Male or female

Exclusion criteria

• Allergy to local anesthetic, Cox2, sulpha drug, acetaminophen or oxycodone
• Women who are pregnant or lactating and women of childbearing age and not following acceptable contraceptive precautions
• Any major medical or psychiatric problem
• Those with a known history of narcotic dependence, abuse or chronic narcotic intake
• Patients with known history of peptic ulcer or GI bleeding in the past, ulcers, congestive heart failure, angina or previous heart attack, coagulation problems, venous thrombosis, kidney or liver disease or strokes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

celebrex

Treatment:

Drug: celebrex

2

Placebo Comparator group

Description:

placebo

Treatment:

Drug: placebo