Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracic Surgery

T

Taipei Medical University

Status

Unknown

Conditions

Video-assisted Thoracoscopic Surgery

Treatments

Procedure: Cervical Vagal Blockade
Procedure: Without Blockade

Study type

Interventional

Funder types

Other

Identifiers

NCT04426097
TMU-JIRB N201803027

Details and patient eligibility

About

Currently, there is a trend toward non-intubated anesthesia methods for video-assisted thoracic surgery in our hospital. During the surgery, intrathoracic vagus nerve blockade is suggested for inhibit cough reflex in previous paper. However, right and left side of vagus nerves both deep near the aorta or trachea respectively. To achieving the procedure may induce cough reflex by lobar traction even result vital organ damage. This study aims to apply alternative vagus nerve blockade at neck level via ultrasound guidance and test if the procedure real reduce cough reflex then previous method. We also follow up the patient's vital sign, vocal cord and diaphragm movement, horner syndrome and hoarseness to evaluating if cervical vagal blockade has the potential risk involve other surrounding nerves

Enrollment

40 estimated patients

Sex

All

Ages

20 to 79 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Adults younger than 80 years old are scheduled for one-port video assisted thoracic surgery

Exclusion criteria

  • Anticipated difficult airway, Respiratory insufficiency,Vocal cord palsy,diaphragm palsy parkinsonism,previous stroke,tachycardia

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

40 participants in 2 patient groups, including a placebo group

Cervical Vagal Blockade
Experimental group
Treatment:
Procedure: Cervical Vagal Blockade
Without Blockade
Placebo Comparator group
Treatment:
Procedure: Without Blockade

Trial contacts and locations

0

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Central trial contact

Lin Jui An, PhD

Data sourced from clinicaltrials.gov

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