Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracic Surgery

Taipei Medical University

Status: Unknown

Conditions: Video-assisted Thoracoscopic Surgery

Treatments: Procedure: Cervical Vagal Blockade; Procedure: Without Blockade

Study type: Interventional

Funder types: Other

Identifiers

NCT04426097

TMU-JIRB N201803027

Details and patient eligibility

About

Currently, there is a trend toward non-intubated anesthesia methods for video-assisted thoracic surgery in our hospital. During the surgery, intrathoracic vagus nerve blockade is suggested for inhibit cough reflex in previous paper. However, right and left side of vagus nerves both deep near the aorta or trachea respectively. To achieving the procedure may induce cough reflex by lobar traction even result vital organ damage. This study aims to apply alternative vagus nerve blockade at neck level via ultrasound guidance and test if the procedure real reduce cough reflex then previous method. We also follow up the patient's vital sign, vocal cord and diaphragm movement, horner syndrome and hoarseness to evaluating if cervical vagal blockade has the potential risk involve other surrounding nerves

Enrollment: 40 estimated patients

Sex: All

Ages: 20 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults younger than 80 years old are scheduled for one-port video assisted thoracic surgery

Exclusion criteria

• Anticipated difficult airway, Respiratory insufficiency,Vocal cord palsy,diaphragm palsy parkinsonism,previous stroke,tachycardia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

Cervical Vagal Blockade

Experimental group

Treatment:

Procedure: Cervical Vagal Blockade

Without Blockade

Placebo Comparator group

Treatment:

Procedure: Without Blockade