Effect of CGF on Postoperative Pain After Third Molar Surgery

Ege University

Status

Completed

Conditions

Oral Complication

Treatments

Other: Concentrated Growth Factor

Other: non-CGF

Study type

Interventional

Funder types

Other

Identifiers

NCT06918327

EGE-DHF-MZ-002

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of concentrated growth factor (CGF) on pain after bilateral impacted third molar surgery and to determine its contribution to the healing process.

The main question it aims to answer is:

Is CGF effective on reducing the pain in impacted third molar surgery? Researchers compare the pain on the CGF-applied and CGF free sides after impacted third molar surgery. Postoperative pain is assessed using the Visual Analogue Scale. TThe postoperative outcomes including pain are clinically assessed at different-time intervals (1-7 days).

Enrollment

49 patients

Sex

All

Ages

18 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients with bilateral, symmetrical, bone-retained (vertical, mesioangular, horizontal) impacted wisdom teeth in the mandible, regardless of gender
Patients without any systemic disease
Patients who have been informed about the duration, purpose and requirements of the study and who have signed the informed consent form voluntarily.

Exclusion criteria

Having a disease affecting general health that requires the application of prophylactic antimicrobial agents
Having a systemic viral, fungal or bacterial infection
Patients with acute or chronic maxillary sinusitis
Suspected or diagnosed pregnancy and nursing mothers
Patients with heart and vascular diseases
Patients with liver disease, haematological disease and neoplastic disease
Patients who have recently received anti-inflammatory therapy
Patients with chronic medication use (antihistamines, NSAIDs, steroids and antidepressants)
Patients predisposed to psychotic or psychopathic tendencies
Patients with rheumatic diseases, blood diseases, diabetes mellitus
Patients at cardiological risk of infective endocarditis
Patients under antibiotic pressure