Effect of Chronic PDE5-Inhibition on Endothelial Function in Diabetics

San Donato Group (GSD)

Status and phase: Completed; Phase 3

Conditions: Diabetes

Treatments: Drug: sildenafil

Study type: Interventional

Funder types: Other

Identifiers

NCT00420901

HSRRM1999/4

Details and patient eligibility

About

chronic PDE5-Inhibition improves endothelial function in diabetics

Full description

Evaluation of endothelial function at baseline and after chronic administration of sildenafil in male subjects with diabetes

Sex: Male

Ages: 35 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• type 2 diabetes
• males

Exclusion criteria

• females, nitrate use, PDE5-Inhibitors intolerance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind