Effect of CI on Prognosis in the Elderly Patients With ACS (CIACS)

Capital Medical University

Status: Unknown

Conditions: Cognitive Impairment; Acute Coronary Syndrome; Elderly

Treatments: Diagnostic Test: MMSE and MoCA

Study type: Observational

Funder types: Other

Identifiers

NCT04278911

BFH--CI and ACS

Details and patient eligibility

About

This study aims to investigate the incidence and characteristics of cognitive Impairment(CI) in the elderly patients with acute coronary syndrome (ACS), and to determine whether CI are predictive of the prognosis of major adverse cardiovascular events (MACE) and mortality.

Enrollment: 500 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ≥65yr
• Confirmed ACS diagnosis （include unstable angina, ST-segment elevation myocardial infarction and Non ST-segment elevation myocardial infarction）
• fulfilled MMSE or MoCA
• patients agreed and provided informed consent

Exclusion criteria

• Type 2 myocardial infarction and Acute nonischemic myocardial injury
• past history of malignant tumors
• Past history of stroke or dementia
• Hepatic insufficiency (ALT>8ULN or ALT>3ULN and TBIL>2ULN)
• Renal insufficiency (GFR<15 ml/min/1.73m2)

Trial design

500 participants in 1 patient group

Participates

Description:

This is an observational study

Treatment:

Diagnostic Test: MMSE and MoCA