Effect of Cinnamon on Glucose and Lipid Levels in Non-Insulin Dependent Type 2 Diabetes Mellitus

University of Oklahoma (OU)

Status and phase: Completed; Phase 2

Conditions: Diabetes Mellitus, Adult Onset

Treatments: Drug: Cinnamon or placebo 500 mg capsule twice daily

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00237640

11798

Details and patient eligibility

About

The purpose of this study is to determine the effects of cinnamon on serum glucose and lipid levels in people with non-insulin dependent type 2 diabetes mellitus.

Full description

Forty people with non-insulin dependent type 2 diabetes mellitus will be randomized to receive either cinnamon or placebo for three months. The dose of cinnamon will be one gram daily. Fasting serum glucose, triglyceride, total cholesterol, LDL, HDL, and insulin levels will be measured at baseline and at 1, 2, and 3 months. HbA1c levels will be measured at baseline and at 3 months. Patients will be monitored for compliance, adverse effects, and dietary changes.

Enrollment: 85 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetes mellitus
• HbA1C > 6.0%
• Age 18 and above
• Able to obtain consent

Exclusion criteria

• Currently taking insulin
• Pregnancy
• End-stage renal disease
• Hemolytic anemia
• Cinnamon intolerance
• Inability or unwillingness to adhere to study protocol

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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85 participants in 2 patient groups, including a placebo group

1

Placebo Comparator group

Treatment:

Drug: Cinnamon or placebo 500 mg capsule twice daily

2

Active Comparator group

Treatment:

Drug: Cinnamon or placebo 500 mg capsule twice daily