ClinicalTrials.Veeva

Menu

Effect of Cisatracurium Versus Atracurium on Intraocular Pressure in Patients Underwent General Anesthesia

I

Isfahan University of Medical Sciences

Status and phase

Completed
Phase 2

Conditions

Intraocular Pressure

Treatments

Drug: cisatracurium
Drug: atracurium

Study type

Interventional

Funder types

Other

Identifiers

NCT01273831
ASD-1213-10

Details and patient eligibility

About

The purpose of this study is to determine which drug makes lower intraocular pressure

Full description

Increase in intraocular pressure (IOP) following tracheal intubation during general anesthesia can be troublesome. The investigators compared the influence of cisatracurium and atracurium on IOP in patients undergoing general anesthesia.

Enrollment

90 patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

ASA class of I or II baseline IOP of lower than 20 mmHg stable hemodynamics no history of ophthalmic diseases not using drugs affecting IOP (e.g. anticholinergics, sympathomimetics) no contraindication for atracurium or cisatracurium administration.

Exclusion criteria

difficulty in mask ventilation or in tracheal intubation end expiratory CO2 of below 35 mmHg or over 45 mmHg O2 saturation of below 90%

Trial design

90 participants in 2 patient groups

atracurium
Other group
Description:
Patients who underwent general anesthesia received atracurium
Treatment:
Drug: atracurium
cisatracurium
Other group
Description:
Patients who underwent general anesthesia received cisatracurium
Treatment:
Drug: cisatracurium

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems