Effect of Cocoa Supplementation in Training Athletes Microbiota and Metabolome

European University

Status: Completed

Conditions: Healthy Athletes

Treatments: Dietary Supplement: cocoa; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT04444388

UEM005

Details and patient eligibility

About

It has recently been suggested that cocoa may improve exercise performance and recovery. This study aim to evaluate the plasma and fecal metabolome after 10 weeks of cocoa supplementation during the training period in recreational athletes to detect possible metabolites involved in the observed benefits of cocoa in athletes

Enrollment: 40 patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-45 years of age
• high physical condition (VO2 ≥ 55 ml/kg/min)
• BMI 18-25 kg/m2

Exclusion criteria

• antibiotics intake during 3 months prior to the study,
• smoking
• nutritional complements
• ergogenic complements
• prebiotics
• probiotics
• vegetarian or vegan diet
• chronic medication
• gastrointestinal surgery
• Any diagnosed disease

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

Cocoa group

Experimental group

Description:

5 g/day of flavonoid-rich defatted cocoa for 10 weeks

Treatment:

Dietary Supplement: cocoa

Placebo group

Placebo Comparator group

Description:

5 g/day of maltodextrin for 10 weeks

Treatment:

Dietary Supplement: Placebo