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Effect of Coffeeberry on Mood, Motivation and Cognitive Performance

PepsiCo logo

PepsiCo

Status

Completed

Conditions

Motivation
Fatigue, Mental
Alertness
Cognitive Performance
Mood

Treatments

Dietary Supplement: Cherry-flavored still beverage
Other: Placebo cherry-flavored still beverage

Study type

Interventional

Funder types

Industry

Identifiers

NCT04974606
PEP-1605

Details and patient eligibility

About

The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of cognitive performance.

Preliminary studies suggest that flavanols and chlorogenic acids can enhance cognitive performance. It is unknown if drinks formulated with flavanols and chlorogenic acids (without high sugar or caffeine) improve cognition or mood to a similar extent as caffeine. Coffeeberry beverage comparisons will be made to a flavored positive control beverage containing caffeine and a flavored placebo beverage.

Enrollment

30 patients

Sex

All

Ages

17 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Are older than 17 and under 50 years of age
  • Self-report of good health

Exclusion criteria

  • Using any prescription medication including birth control
  • Report hypersensitivity to caffeine
  • Have visual impairment that cannot be corrected with glasses or contact lenses
  • Report any food allergies
  • Self-reported excessive leisure time physical activity (> 7 strenuous bouts per week)
  • the presence of current gastrointestinal, sleep, or psychiatric disorder,
  • Report pregnancy/lactation, illegal drug use, smoker
  • failure to demonstrate adequate minimal performance on lab, computer-based cognitive tasks.
  • Participation in another clinical trial within past 30 days

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Quadruple Blind

30 participants in 4 patient groups, including a placebo group

Coffeeberry 100 mg beverage
Experimental group
Description:
Appearance-matched to the other beverages
Treatment:
Dietary Supplement: Cherry-flavored still beverage
Coffeeberry 300 mg beverage
Experimental group
Description:
Appearance-matched to the other beverages
Treatment:
Dietary Supplement: Cherry-flavored still beverage
Placebo beverage
Placebo Comparator group
Description:
Appearance-matched to the other beverages
Treatment:
Other: Placebo cherry-flavored still beverage
Caffeine 75 mg beverage
Active Comparator group
Description:
Appearance-matched to the other beverages
Treatment:
Dietary Supplement: Cherry-flavored still beverage

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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