Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser Treatment

Mahidol University

Status: Completed

Conditions: Hyperpigmentation; Nevus

Treatments: Device: Cold air cooling

Study type: Interventional

Funder types: Other

Identifiers

NCT00287001

185/2005

Details and patient eligibility

About

• To investigate the benefit of epidermal cooling on the incidence of post inflammatory hyperpigmentation after laser irradiation

Full description

• 70% incidence of post inflammatory hyperpigmentation has been reported following a Q-switched nd:YAG laser treatment of acquired bilateral nevus of Ota-like macules.
• We assumed that epidermal cooling may minimize the non-specific injury to the epidermis caused during laser irradiation, leading to the decreased incidence of post inflammatory hyperpigmentation.

Enrollment: 20 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects with acquired bilateral nevus of Ota-like macules.
• At least 18 years old
• No previous treatment on the condition for a minimum period of 1 month.

Exclusion criteria

• Subjects diagnosed of scleroderma, connective tissue disorders, hematologic disorders, hepatitis, infection, or uncontrolled DM
• History of keloid and/or hypertrophic scar.
• Currently on anti-coagulant

Trial design

20 participants in 1 patient group

1

Other group

Description:

1= cool air cooling

Treatment:

Device: Cold air cooling