Effect of Collagen Peptides, in Combination With Resistance Training, on Body Composition and Muscle Strength in Untrained Men

University of Southern Denmark (SDU)

Status: Completed

Conditions: Lean Body Mass; Muscle Strength; Muscle Power; Body Composition

Treatments: Dietary Supplement: Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men; Dietary Supplement: Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men

Study type: Interventional

Funder types: Other

Identifiers

NCT06061315

7260992052

Details and patient eligibility

About

The effect of resistance training with post-exercise Collagen peptides (CP) supplementation on lean body mass, maximal and explosive, isometric muscle strength as well as fat mass, resting metabolism, health parameters and compared to resistance training alone will be evaluated in a group of untrained overweight male (30-60 yrs) population in a randomized controlled trial (RCT).

Full description

Participants will perform supervised resistance training involving (Leg press, pull down, chest press, back extension and abdominal crunches) 3 times a week for 12 weeks. Participants will consume either placebo or collagen peptides (in a double blinded study design) just following resistance training on training days (And approximately the same time of day on non-training days). Prior to, and following 12 weeks of exercise, participants will be tested in body composition, maximal and explosive, isometric muscle strength, resting metabolism, health parameters. Additionally, blood samples will be taken to ensure health and training eligibility and safety.

Participants are healthy untrained overweight males (30-60 yrs)

Enrollment: 80 patients

Sex: Male

Ages: 30 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male, between 30 and 60 years of age
• Fat mass >25 % as measured by bioelectrical impedance analysis
• Stable weight (±5 %) and eating behaviour within the last 3 months.
• Signed informed consent

Exclusion criteria

• Regular physical activity >60 min / week
• Stabile or progressive diseases/conditions (including medication) contraindicating or disabling participation in intensive exercise training and/or with potential to affect training adaptation beyond normal variation. For example:
• Contraindications against physical stress corresponding guidelines of American College of Sports Medicine (ACSM)
• Subjective symptoms during exercise (e.g., unusual physical exhaustion, dyspnoea, nausea)
• Moderate to severe mobility limitation (i.e., due to rheumatic disease)
• Diagnosis of cancer within the last 5 years
• Diabetes mellitus I and II uncontrolled arterial hypertension (systolic blood pressure >155 for mmHg and/or diastolic blood pressure >94 mm Hg; mild hypertension under resting condition will be allowed but such participants will be recommended to consult their general practitioner).
• Conditions contraindicating the supplementation protocol.
• Contraindications against nutritional or ergogenic supplements
• Allergy/aversion against animal protein
• Liver or kidney diseases with a non-permission to ingest certain concentrations of protein.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups, including a placebo group

Collagen peptide group

Experimental group

Description:

This group will consume 1 serving of Collagen peptides, which is produced and marketed ® by GELITA AG, Germany under the brand name BODYBALANC each day.

Treatment:

Dietary Supplement: Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men

Placebo group

Placebo Comparator group

Description:

This group will consume 1 serving of silicon dioxide (Sipernat 350, Evonik, Germany) each day. The product is absorbed in negligible amounts by the intestine and does therefore induce minor metabolic effects.

Treatment:

Dietary Supplement: Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men