Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance (FAT)

Loughborough University

Status: Completed

Conditions: Exercise-induced Inflammation

Treatments: Dietary Supplement: Fish Oil; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03259412

LoughboroughU

Details and patient eligibility

About

The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids [EPA-DHA]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance exercise training study. The investigators aim to establish the potential mechanisms that might mediate performance changes at a cellular level.

Enrollment: 18 patients

Sex: Male

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Males
• Healthy

Exclusion criteria

• Resistance exercise training within the past 6 months
• Vitamin or fish oil supplementation over the past 6 months
• Habitual use of anti-inflammatory drugs
• History of heart disease
• History of coagulation/bleeding disorder
• History of metabolic disease
• Serious allergy
• Known to have blood-borne virus
• Females (Due to differences in cell membrane incorporation of Omega-3 between the sexes and the testing schedule being unable to fit in with menstrual cycle, altering the blood markers that are being measured)
• Currently no symptoms of general illness

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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18 participants in 2 patient groups, including a placebo group

Fish Oil

Experimental group

Description:

Fish oil 5.1g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway

Treatment:

Dietary Supplement: Fish Oil

Placebo

Placebo Comparator group

Description:

Olive Oil 6g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway

Treatment:

Dietary Supplement: Placebo