Effect of Concentrated Growth Factors on Short Implant-Supported Overdentures

Tanta University

Status and phase: Completed; Phase 3; Phase 2

Conditions: Partially Edentulous Patients

Treatments: Radiation: marginal bone loss calculation; Drug: use concentrated growth factor.; Diagnostic Test: testing implant stability

Study type: Interventional

Funder types: Other

Identifiers

NCT06880965

R-OMPDR-8-23-2

Details and patient eligibility

About

The purpose of this study will be to evaluate the effect of concentrated growth factors on stability and radiographic outcome of short implant supported mandibular assisted overdenture

Full description

A controlled clinical trial will be performed upon patients attending the outpatient clinic of Faculty of Dentistry Tanta University.Ten male patients will be selected for this study. Split mouth study design will be used in this study where, Group I represented the right side of the patients' mandibular posterior region will be restored with short implant in place of first molar and Group II represented the left side of the patients' mandibular posterior region will be restored with short implant in place of first molar and concentrated growth factors. The patients will receive partial mandibular assisted overdenture with O-ring attachment on the implant. Stability of implant and Radiographic evaluations will be carried out for every patient at regular recall visits at the time of insertion, 6 and 12 months

Enrollment: 10 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients between 20 to 65 years old. Class I Kennedy's classification Good oral hygiene.

Exclusion criteria

• Bad oral hygiene. Para functional habits ex. (bruxism, clenching,)

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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10 participants in 2 patient groups, including a placebo group

short implants assisted over denture in combination with concentrated growth factors

Active Comparator group

Description:

the left side of the patients' mandibular posterior region was restored with short implant in place of first molar by using short implants assisted over denture with concentrated growth factor.

Treatment:

Diagnostic Test: testing implant stability

Drug: use concentrated growth factor.

Radiation: marginal bone loss calculation

using mandibular posterior short implants assisted over denture without concentrated growth factors

Placebo Comparator group

Description:

the right side of the patients' mandibular posterior region was restored with short implant in place of first molar by using short implants assisted over denture without concentrated growth factor.

Treatment:

Diagnostic Test: testing implant stability

Radiation: marginal bone loss calculation