Effect of Consumption of Black Cumin (Nigella Sativa L.) Water Extract on Weight Loss in Overweight Women

Shahid Beheshti University of Medical Sciences

Status: Withdrawn

Conditions: Obesity

Treatments: Dietary Supplement: Black cumin water extract as a traditional medicine

Study type: Interventional

Funder types: Other

Identifiers

NCT01360957

23911

Details and patient eligibility

About

The purpose of this clinical trial is to study the therapeutic effect of black cumin water extract (Nigella sativa L.) on obesity and overweight

Full description

The worldwide prevalence of obesity has reached epidemic proportions mostly in low-income and transitional than in industrialized countries. Changes in dietary habits and sedentary lifestyles are known to be associated with changes in health and increased prevalence of chronic diseases in the population. The need to promote healthy nutrition for the population must be pursued vigorously, as the escalation of nutrition-related chronic degenerative diseases - once an urban phenomenon - has now spread to the rural population at an alarming rate. During the past decades efficacious strategies have been developed for prevention of these diseases. These strategies involve general lifestyle changes, which include, healthy diet, optimal weight, physical activity, moderate or no alcohol consumption, control of diabetes mellitus and in particular, treatment of obesity. Although the global market for satiety, fat burning and other weight management remedies has been grown, the awareness of the benefits of weight management ingredients is neither sufficient nor clearly perceived by consumer. Subsequently, the opportunities for scientifically-substantiated weight management ingredients regarding the natural and herbal dietary pattern are impressive.

The seed of Nigella sativa (black cumin) is one of the most common traditional herbs for weight loss in the Middle East which is usually used as a spice as well as traditional medicine to treat a variety of health conditions especially inflammatory diseases and obesity.

Furthermore, many of the components present in black cumin including polyphenols have been attributed to have anti-inflammatory and anti-obesity effect which further supports our hypothesis.

Sex: Female

Ages: 16 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being Obese

Exclusion criteria

• Having heart disease or renal disease
• using drugs influencing metabolism and appetite

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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0 participants in 2 patient groups, including a placebo group

Water flavored placebo

Placebo Comparator group

Description:

to be given orally in a dosage of 30 ml trice daily for 60 days

Treatment:

Dietary Supplement: Black cumin water extract as a traditional medicine

Black cumin water extract as a traditional medicine

Experimental group

Description:

Black cumin water extract as a traditional medicine to be given orally in a dosage of 30 ml trice daily for 60 days

Treatment:

Dietary Supplement: Black cumin water extract as a traditional medicine