Effect of Controlled Ovarian Stimulation in Quality of Oocyte and Embryo

Minia University

Status and phase: Unknown; Phase 2

Conditions: Ovarian Stimulation

Treatments: Drug: HHMG

Study type: Interventional

Funder types: Other

Identifiers

NCT04539067

635_5/2020

Details and patient eligibility

About

Investigate and compare the efficacy of H FSH plus HMG Vs HMG alone on oocyte and embryo quality in IcsI patients

Full description

70 patients divided in to 2groups Group A controlled ovarian stimulation with H FSH and HHMg Group B controlled ovarian stimulation with HMG alone Results will be discussed later

Enrollment: 70 estimated patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Infertil women aged from 20_35yr
2. Normal utreus
3. Normal ovaries
4. unexplained infertility
5. no endometriosis

Exclusion criteria

1 - poor responders to gonadotropin 2-Prior history of more than 3unsucceful ICSI 3-Any malformation of sexual organs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

HMG group

Experimental group

Description:

Induction of ovulation from 2nd day of cycle Follow diameter of follicle When follicle 18:22mm Receive HMG

Treatment:

Drug: HHMG

H FSH plus HHMG

Experimental group

Description:

Follow up ovulation from the 2nd day to 5th of menstruation cycle When follicle diameter 18mm to 22mm made induction of ovulation

Treatment:

Drug: HHMG