Effect of Corona Virus on Intravitreal Injections

Benha University

Status: Enrolling

Conditions: Choroidal Neovascularization; Age-Related Macular Degeneration; Diabetic Macular Edema; Myopic Choroidal Neovascularisation; Diabetic Retinopathy

Treatments: Drug: Anti-vascular endothelial growth factors (Anti-VEGFs)

Study type: Interventional

Funder types: Other

Identifiers

NCT05494775

Rc-11-2022

Details and patient eligibility

About

During pandemic of corona virus, patients compliance may be affected. We aim to study the factors lead to unregulated visits and its implications on the final visual outcome.

Full description

The corona virus pandemic may affects patients regular visits to ophthalmic clinic, we aim to study the sequel of the pandemic on intravitreal injections results in diabetic macular edema, wet age related macular degenerations, myopic choroidal new vascularization, and proliferative diabetic retinopathy.

Enrollment: 250 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with the following conditions (diabetic macular edema, wet age related macular degeneration, myopic choroidal new vascularization and retinal vein occlusion complicated with macular edema).

Exclusion criteria

• patients that are known to have hypersensitivity to Anti-VEGFs.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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250 participants in 4 patient groups

Diabetic macular edema

Active Comparator group

Description:

Cases with diabetic macular edema that are prepared for intravitreal injection of anti-vascular endothelial growth factors.

Treatment:

Drug: Anti-vascular endothelial growth factors (Anti-VEGFs)

Wet age related macular edema

Active Comparator group

Description:

Cases with wet age related macular degenerations that are prepared for intravitreal injection of anti-vascular endothelial growth factors.

Treatment:

Drug: Anti-vascular endothelial growth factors (Anti-VEGFs)

Retinal vein occlusion

Active Comparator group

Description:

Cases with macular edema secondary to retinal vein occlusion that are prepared for intravitreal injection of anti-vascular endothelial growth factors.

Treatment:

Drug: Anti-vascular endothelial growth factors (Anti-VEGFs)

Myopic choroidal new vascularization

Active Comparator group

Description:

Cases with myopic choroidal new vascularization that are prepared for intravitreal injection of anti-vascular endothelial growth factors.

Treatment:

Drug: Anti-vascular endothelial growth factors (Anti-VEGFs)