Effect of Corticosteroid Injections on Blood Glucose (CSI)

Duke University

Status and phase

Suspended

Phase 2

Conditions

Shoulder Osteoarthritis

Hip Osteoarthritis

Diabetes Mellitus

Steroid Diabetes

Knee Osteoarthritis

Adhesive Capsulitis

Treatments

Drug: Dexamethasone 4mg

Drug: Kenalog 40 MG

Drug: Celestone

Drug: Depo-medrol

Study type

Observational

Funder types

Other

Identifiers

NCT05048264

Pro00108093

Details and patient eligibility

About

The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee and hip joints in diabetic patients on resultant blood glucose readings.

Full description

The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee, and hip joints in diabetic patients on resultant blood glucose readings.

Corticosteroid injections (CSI) are frequently used in orthopedic settings in order to treat a wide array of orthopedic issues, including osteoarthritis, bursitis, tendinitis, and many others. The effect of diabetes on the musculoskeletal system and its role in orthopedic disease has been well-documented. Current evidence demonstrates that corticosteroids, even when administered through a local musculoskeletal injection, can lead to temporary increases in blood glucose. Ultrasound guidance was not explicitly used in any of the studies examining the impact of steroids on blood glucose. The utilization of ultrasound guidance has been shown to increase accuracy when performing injections into the subacromial space as well as the glenohumeral joint when compared to palpation/landmark-guided injections.

Enrollment

55 estimated patients

Sex

All

Ages

40 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Known diabetic patients ages 40-75 undergoing clinically indicated standard of care corticosteroid shoulder, knee and hip joint injection
Ability to perform daily blood glucose testing
Can receive and send text messages

Exclusion criteria