Effect of Cryotherapy on Postoperative Pain in Vital Pulp Treatment of Molar Teeth

Çukurova University

Status: Completed

Conditions: Pulpitis - Irreversible

Treatments: Other: Cryotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT06644703

10.05.2025/144

Details and patient eligibility

About

The goal of this clinical trial was to evaluate the effect of cryotherapy with salin solution on the intensity of postoperative pain after total pulpotomy procedures in molar teeth with symptomatic irreversible pulpitis. The main question it aims to answer is:

• Does controlled irrigation with cold saline in total pulpotomy reduce the severity of postoperative pain? In the cryotherapy group, unlike the control group, after hemostasis was achieved, the coronal pulp cavity was irrigated with 2 °C saline solution for 5 minutes.

Enrollment: 62 patients

Sex: All

Ages: 14 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Teeth with

• moderate or severe pain
• diagnosed with symptomatic irreversible pulpitis
• no tenderness to percussion and palpation
• positive response to cold test and electric pulp test
• no signs of periapical pathology

Exclusion criteria

Teeth which

• could not be restored or required post-core
• had periapical lesions,
• had poor periodontal status (pocket depth> 4 mm),
• had negative responses to pulp sensitivity tests,
• had no pulp exposure after caries removing Patients who
• had no preoperative pain or had mild preoperative pain
• had bleeding disorders
• had systemic diseases such as immunosuppressive disease or diabetes

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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62 participants in 2 patient groups

Cryotherapy group

Experimental group

Description:

After the coronal pulp tissue was completely removed up to the root canal orifice with a high-speed sterile diamond bur under water cooling, hemostasis was achieved within 8 minutes using a cotton pellet moistened with 1% NaOCl. The pulpotomy area was irrigated with 2 °C saline solution for 5 minutes. Then, the pulp chamber was covered with 2-3 mm thick Bio MTA+ (Cerkamed Company, Poland) and composite restoration of the teeth (Clearfil Majesty Posterior, Kuraray Medical Inc, Tokyo, Japan) was completed in the same visit.

Treatment:

Other: Cryotherapy

Control group

No Intervention group

Description:

After the coronal pulp tissue was completely removed up to the root canal orifice with a high-speed sterile diamond bur under water cooling, hemostasis was achieved within 8 minutes using a cotton pellet moistened with 1% NaOCl. Then, the pulp chamber was covered with 2-3 mm thick Bio MTA+ (Cerkamed Company, Poland) and composite restoration of the teeth (Clearfil Majesty Posterior, Kuraray Medical Inc, Tokyo, Japan) was completed in the same visit.