Effect of Cumulative Chloride Dose on Development of Acute Kidney Injury in Critically Ill Children

Stanford University

Status: Withdrawn

Conditions: Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT02188602

27752

Details and patient eligibility

About

The investigators would like to investigate the effect of chloride dosing on the development of acute kidney injury in critically ill patients. The investigators hypothesis is that administering intravenous fluids with higher chloride content are more likely to lead to acute kidney injury.

Full description

Retrospective chart review from 2008-2012 evaluating chloride dosing and serum chloride levels and their effects on acute kidney injury in the pediatric ICU. Patients will be included for the first seven days of their PICU stay.

Sex: All

Ages: 1 month to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age less than 18 years
• PICU admitting diagnosis of sepsis, respiratory failure, or hepatic failure.

Exclusion criteria

• hyponatremia or hypernatremia at PICU admission
• preexisting diagnosis of End-stage renal disease or renal transplant
• presence of neurologic comorbidities.

Trial design

0 participants in 2 patient groups

High Chloride Dose

Description:

Patients receiving high dosing of chloride

Low Chloride Dose

Description:

Patients receiving low dosing of chloride