Effect of Daily Steps on Fat Metabolism

The University of Texas System (UT)

Status: Completed

Conditions: Atherosclerosis; Metabolic Syndrome

Treatments: Behavioral: Low Steps; Behavioral: Moderate Steps; Behavioral: Very Low Steps

Study type: Interventional

Funder types: Other

Identifiers

NCT03697382

2018-08-0031

Details and patient eligibility

About

Reduced ambulatory activity has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of varying levels of daily ambulation on response to a HFTT after an acute aerobic exercise bout.

Enrollment: 12 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Exclusion Criteria:

• Cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
• Respiratory problems
• Musculoskeletal problems that prevent prolonged sitting or exercise
• Obesity
• Susceptibility to fainting
• Pregnancy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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12 participants in 3 patient groups

Very Low Steps

Experimental group

Description:

Subjects will be asked to undergo reduced daily stepping to a level of 2,500 steps/d for 2 days. On the evening of day 2, they will be asked to run at 65% of VO2max for 1-hour.

Treatment:

Behavioral: Very Low Steps

Low Steps

Experimental group

Description:

Subjects will be asked to undergo reduced daily stepping to a level of 5,000 steps/d for 2 days. On the evening of day 2, they will be asked to run at 65% of VO2max for 1-hour.

Treatment:

Behavioral: Low Steps

Moderate Steps

Experimental group

Description:

Subjects will be asked to undergo reduced daily stepping to a level of 7,500 steps/d for 2 days. On the evening of day 2, they will be asked to run at 65% of VO2max for 1-hour.

Treatment:

Behavioral: Moderate Steps