Effect of Deep Brain Stimulation on Lower Urinary Tract Function

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Urinary Tract Disease; Movement Disorder

Treatments: Procedure: deep brain stimulation ON; Procedure: Deep brain stimulation OFF

Study type: Interventional

Funder types: Other

Identifiers

NCT00610233

KEK 33/05

1005

Details and patient eligibility

About

The precise mechanisms underlying cerebral regulation of lower urinary tract (LUT) function are still poorly understood. Patients with deep brain stimulation (DBS) offer the unique opportunity to investigate the role of different cerebral centers on LUT function.

We hypothesize that DBS has a significant effect on LUT function and that these effects depend on the specific stimulated cerebral center.

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with deep brain stimulation (DBS)

Exclusion criteria

• Pregnancy
• Age <18 years

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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45 participants in 2 patient groups

A

Active Comparator group

Description:

Urodynamic investigation with deep brain stimulation ON

Treatment:

Procedure: deep brain stimulation ON

B

Experimental group

Description:

Urodynamics with deep brain stimulation OFF

Treatment:

Procedure: Deep brain stimulation OFF