Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF

Tang-Du Hospital

Status: Unknown

Conditions: Embryo

Treatments: Device: 140 microns denuding pipette; Device: 150 microns denuding pipette

Study type: Interventional

Funder types: Other

Identifiers

NCT03810040

123456

Details and patient eligibility

About

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Full description

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. The participants were divided into two group. Odd-numbered days the zygotes were degranulated with the 140 microns needles. Even-numbered days the zygotes were degranulated with the 150 microns needles. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Enrollment: 400 estimated patients

Sex: Female

Ages: 22 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• first cyele of IVF treatment

Exclusion criteria

• oocyte number less than 4
• oocyte number over than 25

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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400 participants in 2 patient groups

Odd-numbered days

Active Comparator group

Description:

Once odd-numbered days the zytoges of IVF cycle were collected. The 140 microns denuding pipette was used.

Treatment:

Device: 140 microns denuding pipette

Even-numbered days

Experimental group

Description:

Once even-numbered days the zytoges of IVF cycle were collected. The 150 microns denuding pipette was used.

Treatment:

Device: 150 microns denuding pipette