Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery

Federico II University

Status: Completed

Conditions: Post Partum Hemorrhage

Treatments: Other: delayed cord clamping

Study type: Interventional

Funder types: Other

Identifiers

NCT04353544

1/04-18OST

Details and patient eligibility

About

Policies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds aLer birth, whereas latercord clamping usually involves clamping the umbilical cord greater than one minute after the birth or when cord pulsation has ceased

Enrollment: 122 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• singleton pregnancy
• at term
• cephalic presentation
• spontaneous labor
• spontaneous vaginal delivery

Exclusion criteria

• multiple gestation
• preterm gestation
• induced labor
• operative delivery
• hypertension or preeclampsia
• fetal anomaly
• abnormal placentation
• planned cord blood banking
• maternal bleeding disorder

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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122 participants in 2 patient groups

Immediate cord clamping

Active Comparator group

Description:

Immediate cord clamping was defined as clampingwithin 15 seconds of birth

Treatment:

Other: delayed cord clamping

delayed cord clamping

Experimental group

Description:

when the cord stopped pulsing, or five minutes

Treatment:

Other: delayed cord clamping