Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction

Baskent University

Status

Completed

Conditions

Stem Cell

Periodontal Pocket

Third Molar

Treatments

Procedure: L-PRF

Procedure: L-PRF + DPSC

Study type

Interventional

Funder types

Other

Identifiers

NCT04641533

SecilC

Details and patient eligibility

About

The purpose of this study is to compare the clinical and radiographic effectiveness of Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF combined with dental pulp stem cell (DPSC) application to the extraction socket of mandibular third molars.

Full description

Patients aged between 18 and 30 years, seeking for bilateral impacted LM3 extraction surgeries and meeting eligibility criteria were included to the study. At baseline right and left impacted third molars (LM3s) were randomly assigned to one of the treatment group (L-PRF and L-PRF + DPSC). Baseline and 6th month clinical and radiographic measurements were compared.

Enrollment

13 patients

Sex

All

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients aged between 18 and 30 years
Bilateral impacted LM3 extraction surgeries requirement

Exclusion criteria

Having clinical signs or symptoms of abscess or cellulitis formation
Having a history of radiotherapy
Having any systemic diseases interfering with wound healing and/or smokers
Patients who had been diagnosed as periodontitis
Patients who had LM2s with caries or restorations that have an unidentifiable cementoenamel junction